Common Complications in Polycystic Kidney Disease(PKD)

Polycystic Kidney Disease is well known as a genetic kidney disorder. Patients with PKD develop numerous cysts in the bilateral kidneys. The cysts can increase in size over long periods of time and may cause the following complications.
What are the common complications in PKD?
1. Cysts in other organs
Many patients with ADPKD will develop liver cysts during their lifetime. Generally, incidence of liver cysts increase over time.
There is often an increase in liver size, but liver tissue function stays fairly constant. Women who have been pregnant are more likely to have liver cysts; and the cysts are more numerous and larger in women who have been pregnant compared to women who have not been pregnant. Besides the liver, other organs such as spleen, pancreas, vasculature, testes and intestines can also be affected.
2. Cardiovascular complications
Cardiovascular complications in PKD mainly include high blood pressure, cerebral aneurysms and mitral valve prolapse (MVP), a condition where the valve separating the top and the bottom of the left side of the heart does not close properly. Sometimes this causes blood to leak back to the top part of the heart, which is called regurgitation or a heart murmur. MVP occurs in approximately 26% PKD patients. MVP can result in palpitations sensations.
3. 5%-10% of patients with POKD are at risk of intracranial aneurysms; in incidence increases in those with a family history of aneurysms. An aneurysm is an out-pouching in a blood vessel. Intracranial aneurysms occur in the blood vessels of the brain. Aneurysms can leak or rupture. A ruptured aneurysm can I result in such symptoms as severe headache, pain in moving the neck, nausea and vomiting, and even loss of consciousness. All such symptoms require immediate medical attention.
4. Gastrointestinal complications
Gastrointestinal complications include diverticulosis. Diverticula are out-pouchings of the large intestine (colon).PKD patients on dialysis or have had a transplant are more likely to suffer from diverticula and have more complications from diverticula, including infection (divertiulitis), than people who have other kidney diseases.
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Complications of Congenital Polycystic Kidney Disease

Polycystic kidney disease is a hereditary kidney disease due to multiple cysts in the cortex and medulla of the kidney, polycystic kidney disease is a result in many complications of the disease, disease treatment is very difficult in advance to detect the disease early treatment conducive to control the disease, polycystic kidney disease have a common complication?
For many people who have polycystic kidney disease family history, it is necessary to know what are about the disease's complications. Understanding of this area, so that future in the face of this disease, better treatment, allowing the disease to get better control.
First of all, presumably a lot of people have polycystic kidney disease is a hereditary kidney disease, polycystic kidney complications is one of the most concern. Mainly the performance of multiple or numerous sizes fluid cysts in both kidneys. Deepening understanding of the scientific progress of this disease, the prognosis is significantly improved. The course of treatment often polycystic kidney complications. That polycystic kidney complications, what does?
1, the cyst infection: general many cases can cause kidney pain and tenderness, and fever. To identify this disease infection or pyelonephritis is not easily line gallium scan photography would be helpful at this time.
Hematuria: there is this aspect, but very few cases, there may be activities persistence of gross hematuria, and even life-threatening.
3, high blood pressure or repeated urinary tract infections and other complications, also need attention.
4, kidney stones: Under normal circumstances, the polycystic kidney back pain is generally dull prompted concurrent kidney stones, cramps and accompanied by gross hematuria.
Cerebral arterial circle Angioma: Under normal circumstances, we need to know complicated by the vascular tumor by 10% to 40%, often due to vascular aneurysm, cerebral hemorrhage further examination was found. In addition, the thoracic aortic aneurysm and valvular heart disease (such as valvular regurgitation and prolapse) are more common. May be associated with portal hypertension and alveolar dysplasia in infantile polycystic kidney disease.
6, multiple cysts of other organs: experts say, middle age found in polycystic kidney disease patients, about half have polycystic liver disease after the age of 60, about 70%. Is generally believed that their development is slower, and more about polycystic kidney disease 10 years later. The cyst expansion is made by the lost bile duct. In addition, pancreas and ovaries may be complicated by the cyst, colonic diverticulitis complicated by a higher rate.
Pyelonephritis: In addition to the above, in this regard is also a common complication of polycystic kidney disease, the reason is not clear. The symptoms of pus in urine with little or no. Smear or quantitative culture of diagnosis can be made. Citrate 67Ga scan photography to determine the site of infection, including the location of the abscess.

Complications of PKD

Simple renal cyst may develop into malignancy cyst, but the morbidity is rather low. Actually, if being treated in time, Polycystic Kidney Disease can be controlled under a stable condition. There are many people refuse to have treatment when the cyst is small, and once they are hurt by the pain cause by cysts, they come to hospital and find the cyst already big enough and hard to be treated. So, for simple renal cyst, paying much attention to the disease condition does matter a lot. However, for PKD, with the growing of cysts, functional cells and tissues in kidney will be damaged, so we can say that PKD is much more serious because when the cells are damaged, there will be problems with kidney functions, and if no treatment, finally the disease may deteriorate into ESRD. Renal Failure caused by PKD is very common among those who are undergoing dialysis. And PKD does arouse many complications as follows.

1. Kidney stone and cyst calcification. For patients with PKD, when they feel painful in low back, especially when the pain become serious, and blood in urine can be seen by the naked eyes, it needs to be considered as kidney stone, and the sufferers had better take some related examinations to make sure the disease condition.

2. Cysts cancerization. It is still disputed whether renal cysts can lead to cancerization, but actually there really some people getting cancerization as an aftermath of renal cysts. When the patients have pain in renal region, regular hematuria, loss of weight, blood coagulation, and abnormal anemia, or the increase of blood cells, cancerization can be one accompanying disease they must pay close attention to. What they need to do is CT scan or some related examinations to detect the condition of cysts.