Polycystic Kidney Disease - Kidney Disease Hospital

Polycystic Kidney Disease (PKD) is an inherited disease which can be divided into two kinds including Autosomal Dominant PKD and Autosomal Recessive PKD. Both men and women are at a risk to get the disease if they are in a family with the history of PKD.
● Autosomal Recessive PKD (ARPKD) mainly occurs in infants, and can lead them die in a very early age, and a few part of them can survive their childhood and little of them can keep alive until their adulthood. Even though ARPKD is a kind of inherited disease, neither of the children’s parents may have symptoms in their whole life. In addition, ARPKD is rare in clinic.
● Autosomal Dominant PKD (ADPKD) is always found in adult even though people in any ages may get the disease. It is so common that 5%-10% of the patients with it are at risk to get end stage of Chronic Kidney Disease. Patients with ADPKD are likely to have the symptoms of renal cyst, hematuria, proteinuria and high blood pressure and so on.
Patients get ADPKD from their parents, which means that they are carrying the factors of the disease from the very beginning of their life, but their disease can be found after they grow up. ADPKD can attack a family easily due to its character of heredity. Half of the children may have the disease if one of the parents has PKD, and the percentage will get up to 75% if both of parents have the disease. This is also a key factor which should be noticed, if one of the family members has PKD, other members should be careful and try to delay the occurrence of it.
Recent years, more and more people began to pay attention to the avoiding of the disease which helped a lot to have a better prognosis after accepting a treatment.
Both kinds of polycystic kidney disease can cause agony for a whole family, and even from generation to generation, therefore, an effective and fundamental treatment is very important for them.  Kidney Disease hospital has made great improvement in treating PKD in recently years, and you can find more information in our website.

What are the Symptoms of Polycystic Kidney Disease?

Polycystic Kidney Disease (PKD) is a kind of genetic disease which is quite common in clinic. It refers to the numerous cysts in both kidneys which are fluid-filled and distribute symmetrically. In order to have proper precaution in advance, it is important for everyone to know more about Polycystic Kidney Disease and especially its commonsymptoms.
☆ Swelling in kidney. The disease condition of both kidney differs from each other. The two kidneys will have different sizes and they can occupy all the space in abdomen in the later period of the disease. There are many cysts in the kidney, so the kidney will have irregular shapes and a hard texture.
☆ Pain in renal region. Usually the sufferers will have pressed feeling and dull pain in loin or abdomen. The pain will appear or aggravate after hard work, long-time walking and sitting, and it will release after a rest in bed.
☆ Hematuria. About half of the sufferers will have microscopic hematuria, and sometimes it is gross hematuria. Hematuria is caused by the rupture of blood vessels in cysts' wall, and it is always accompanied with proteinuria, but the volume of urinary protein is small (<1.0g/d). Besides, the pyuria will be obvious when there is infection in the kidney.
☆ Hypertension. Before the increase of serum creatinine, half of sufferers will have Hypertension. It is related to the renin-angiotensin-aldosterone system (RAAS). Hypertension will have influence on the prognosis of sufferers with renal cysts.
☆ Renal insufficiency. Generally speaking, only a few people can have renal insufficiency in the age younger than 40, and about half of the sufferers with PKD will retain their renal function at the age of 70. However, in some cases, the sufferers will deteriorate into renal failure during the adolescence.
☆ Polycystic liver. People who are diagnosed as ADPKD in their middle ages are usually accompanied with Polycystic Liver. Generally speaking, polycystic liver will appear 10 years later after PKD. Besides, sometimes there may be cysts in pancreas and ovary as well.
There are all the common symptoms of Polycystic Kidney Disease. I hope all the information above can be helpful for you. PKD is a genetic disease, so if you have the familial history of PKD, you should have examinations regularly. As long as you have some clinical symptoms, you had better go and see a doctor in order to have a proper treatment in time. If you have any questions, you are welcome to talk with our consultant online or leave a message to ckdsite@hotmail.com .