I Operation only focus on symptoms, ignores the fundamental causes. Both drainage and pressure relief treatment point at the cysts with lager size, and have nothing to do with the small ones. Moreover, when the inter pressure is reduced, the small cysts will grow dramatically without the previous pressing. Then the patients will fell into a loop, cysts grow with the relief of pressure, and damage of kidney is aggravated along with application of drainage.
II Nephrectomy: Apart from the high expenditure of it, it may also arouse serious consequence. Firstly, as nephrectomy is a major operation, it is really a challenge for the patients’ endurance that has already been exhausted by PKD. Secondly, PKD is a hereditary disease, abundance of one kidney may not stop the damage to the other kidney. What’s worse, it may make renal functions of the preserved kidney decline rapidly.
III Kidney Transplant：First of all, the expenditure is not affordable to most of patients. Then, the patients may have to wait a quite long time for the right kidney source, but few of patients are lucky enough to wait till the day comes. Last but not the least, rejection after the transplant is a big concern, which may bring death.
IV Effects of Assistant Drug: For example, converting enzyme inhibitor is a widely used among the patients with PKD, for Hypertension is a common complication for those patients. Though it has a good effect to control the blood pressure, it also brings damage to the kidney. Especially for those have big kidneys, converting enzyme inhibitor may cause severe renal hemorrhage and sharp decline of renal function, and even shock, which threatens the patients’ lives. Besides, long-term application of these drugs will cause drug-resistance, bringing irreversible damage to liver.
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