2012-07-31

Common Symptoms of Polycystic Kidney Disease in early

Polycystic kidney disease is a common hereditary disease, many patients want to know more knowledge of the polycystic kidney disease, first of all we talk about from the symptoms of polycystic kidney, is an external manifestation of the disease because the symptoms, we can know the patient's disease to the extent that the external manifestations of the patients. Then the common symptoms of polycystic kidney disease?
Polycystic kidney disease is generally divided into adult polycystic kidney disease with infantile polycystic kidney disease. Adult polycystic kidney disease symptoms usually in early adulthood, often with hematuria, hypertension or renal insufficiency onset, abdominal palpation can be found in the larger polycystic kidney disease, renal function mostly slow progressive loss, hypertension, obstructive or pyelonephritis, is an important reason to accelerate renal damage, autosomal recessive type (infantile) polycystic kidney disease in infancy, clinical relatively rare, more than died in infancy, a very small number of mild to survive to adulthood.
The common symptoms of adult polycystic kidney disease :
1, back pain
Internal or flank pain is one of the polycystic kidney disease the most common early symptoms, the occurrence frequency with age and cyst increases, women are more common. Often lower back pressure or dull pain, and sometimes abdominal pain, the pain may be physical activity, walking for too long, sedentary exacerbated after bed rest can reduce bleeding of renal stones move or infection is also sudden drama the reason of the pain. Acute pain or pain flare often prompts the cysts rupture, stones or blood clots caused by urinary tract obstruction, often accompanied by fever. Chronic pain, enlarged kidneys or cysts stretch renal capsule, renal pedicle, and compress the adjacent organs or interstitial inflammation. The huge hepatic cysts can cause under the right rib pain.
2, chronic renal failure
Leading cause of death in polycystic kidney disease. Early impairment of renal concentration function decline. With normal renal function in patients with adult polycystic kidney disease maximum urine osmolality of 16% lower than the maximum urine osmolality of normal family members, and age is gradually declining.
3, high blood pressure
Hypertension is the most common early manifestation of polycystic kidney disease, the level of blood pressure and kidney size, cyst number of proportional increases with age increasing. Hypertension is a risk factor to promote the deterioration of renal function.
4, anemia
Not the development of polycystic kidney disease patients are usually without anemia.Patients with persistent hematuria may have mild anemia. Another 5% of patients stimulate the renal interstitial cells Epo increase due to ischemia caused by polycythemia. When the progression to ESRD stage renal failure in patients with polycystic kidney disease patients compared with other causes of anemia appears later and to a lesser degree.
5. Hematuria
About half of the patients showed microscopic hematuria may have episodes of gross hematuria, this Department of the cyst wall rupture of blood vessels due to bleeding for a long time can cause blood clots through the ureter colic, hematuria, often accompanied by white blood cells in urine and proteinuria, urinary protein less , usually no more than 1.0g / d, renal infection, pyuria obvious, hematuria aggravated, low back pain with fever.
6, renal enlargement
Both sides of the nephropathy progress asymmetry, the size difference, to the late two kidney occupies the entire abdominal cavity, the kidney surface cloth has a lot of cysts, kidney-shaped irregular, uneven, hard texture.
6, polycystic liver disease
Polycystic liver about half have polycystic liver disease after the age of 60, about 70% is generally believed that the slower development and less about polycystic kidney disease 10 years later, the cyst is made by the lost bile duct dilatation, pancreatic and ovariancan be cysts, high complication rate of colonic diverticulitis.

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