High creatinine level and high urea nitrogen in PKD

why do people with Polycystic Kidney Disease have high creatinine level and high urea nitrogen?
Both creatinine and urea nitrogen are the wastes produced by our body. In normal cases, the level of creatinine in the blood and the level of urea nitrogen in the blood are kept in a stable range. When there are excessive creatinine and urea nitrogen, kidneys play their excretion function, as a result of which, creatinine level and urea nitrogen level are reduced to the normal range again. However, Polycystic Kdney Disease damage kidneys and make them unable in displaying excretion function, because of which, excessive creatinine and excessive urea nitrogen pile up in the blood. Consequently, creatinine level and urea nitrogen increase.
According to clinical studies, creatinine level does not increase until a half of kidney function decrease. Therefore, increased creatinine level indicates kidneys have been damaged by Polycystic Kidney Disease seriously.
Aside from creatinine and urea nitrogen, there are mny toxic wastes in the blood. As kidneys are failed in excreting them, they pile up in the blood and damage our other organs. Usually, the higher the creatinine level and urea nitrogen level are, the more toxins in the blood and the more likely that the other organs are damaged. This is the reason why kidney failure patients are recommended to start dialysis when theri creatinine level increases to a certain level.
At the moment, only Micro-Chinese Medicine Osmotherapy shows better treatment effects in treating Polycystic Kidney Disease. Micro-Chinese Medicine Osmotherapy occurs on the basis of Chinese herbal treatment. It is natural and causes no side effects. Therefore, it is very popular among Polycystic Kidney Disease patients.